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Wednesday, July 29, 2020 | History

2 edition of Selected abstracts on animal models for biomedical research. found in the catalog.

Selected abstracts on animal models for biomedical research.

Institute of Laboratory Animal Resources (U.S.)

Selected abstracts on animal models for biomedical research.

by Institute of Laboratory Animal Resources (U.S.)

  • 90 Want to read
  • 23 Currently reading

Published by National Academy of Sciences in Washington .
Written in English

    Subjects:
  • Disease Models, Animal -- Bibliography.

  • Edition Notes

    Statement[Compiled and edited by Charles B. Frank and Marilyn J. Anderson.]
    GenreBibliography.
    ContributionsFrank, Charles B., comp., Anderson, Marilyn J., comp.
    The Physical Object
    Paginationv.
    ID Numbers
    Open LibraryOL17839635M

    Selected Abstracts on Animal Models for Biomedical Research You will receive an email whenever this article is corrected, updated, or cited in the literature. You can . Use of animal models in biomedical research People often ask how the use of animals in experiments can be justified when animals are clearly so different from humans. The answer is that animals are used in specific areas of research where they do not differ from humans for the characteritics being studied, and where the differences are of no.

    For many scientific experiments, the answer to those questions will be the domestic dog, Canis familiaris. The size, biologic features, and cooperative, docile nature of the well-socialized dog make it the model of choice for a variety of scientific inquiries. The contributions of the dog to human health and well-being are numerous (Gay, ). Simple Summary. Biomedical journals have the responsibility to promote humane research. To gauge and evaluate journal policies on animal research, the EXEMPLAR—For “Excellence in Mandatory Policies on Animal Research”—scale is presented and applied to evaluate a sample of biomedical journals, providing an overview of the current landscape of editorial policies on the ethical.

      To capture the translational potential of publications across the entire biomedical research landscape, we adapted an algorithm that maps papers on a trilinear graph by using 3 overarching branches of the MeSH ontology: Human, Animal, and Molecular/Cellular (HAMC; “the triangle of biomedicine” ; Fig 1B). Almost all NIH-funded papers (>96%. Get this from a library! Using animal models in biomedical research: a primer for the investigator. [Pierce K H Chow; Robert T H Ng; Bryan E Ogden;] -- Animal models play crucial roles in the continuum of experimental activities that make up biomedical research. Such in vivo modes are especially important in proof-of-principle experiments and in.


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Selected abstracts on animal models for biomedical research by Institute of Laboratory Animal Resources (U.S.) Download PDF EPUB FB2

Download a PDF of "Selected Abstracts on Animal Models for Biomedical Research - III" by the National Research Council for free. Download a PDF of "Selected Abstracts on Animal Models for Biomedical Research - III" by the National Research Council for free.

A PDF is a digital representation of the print book, so while it can be loaded. Suggested Citation:"Appendix."National Research Council. Selected Abstracts on Animal Models for Biomedical Research - gton, DC: The National. Suggested Citation:"Alimentary System."National Research Council. Selected Abstracts on Animal Models for Biomedical Research - gton, DC:.

The publication is the second in a series containing abstracts selected from the biomedical literature pertaining to animal models. These abstracts were accumulated during and represent only a select portion of papers appearing in journals during the period - In addition to the abstracts presented in this compendium, a special section has been appended that includes a brief Cited by: 1.

Books to Borrow. Top American Libraries Canadian Libraries Universal Library Community Texts Project Gutenberg Biodiversity Heritage Library Children's Library.

Open Library. Featured movies All video latest This Just In Prelinger Archives Democracy Now. Occupy Wall Street TV NSA Clip Library. There are many types of models used in biomedical research, e.g., in vitro assay, computer simulation, mathematical models, and animal models. Vertebrate animals represent only a fraction of the models used, yet they have been responsible for critical research advancements (National Research Council, ).

Abstract. The first years of the 21 st century have seen an unparalleled progress in biomedical sciences. Several dogmata that haunted scientific debate for decades were easily abandoned, and there is a fundamental shift away from eminence-based toward evidence-based assessment of preclinical models, probing their true value in predicting clinical outcomes of human diseases.

To accomplish this, we need robust animal models that incorporate the same level of genetic and genomic variation as highly diverse human populations. A key goal of biomedical research is to provide clinicians with sufficient knowledge to predict disease risk and choose effective treatment.

Animal Models for the Study of Human Disease, Second Edition, provides needed information on model sharing, animal alternatives, animal ethics and access to databanks of models, bringing together common descriptions of models for busy researchers across biomedical and biological sciences.

Offering easily searchable advantages and disadvantages for each animal model and organized by. Experimental animal models in biomedical resarch / Robert Ng.

Nonhuman primates as models in biomedical research / Jason Vilano and Bryan Ogden -- ch. Regulatory considerations in the use of animal models. Laws, regulations and guidelines for biomedical research in Singapore / Boon Theng Kuah. Animal Models for the Study of Human Disease, Second Edition, provides needed information on model sharing, animal alternatives, animal ethics and access to databanks of models, bringing together common descriptions of models for busy researchers across biomedical and biological sciences.

Animal-based research has been accepted as the 'gold standard' approach for preclinical biomedical research and testing since the second half of the 20th century.

Abstract. Neuroanatomy provides a solid basis for identifying and manipulating the neuronal circuits underlying brain functions.

The common marmoset (Callithrix jacchus) is a relatively new primate model used in a broad range of biomedical research fields, including marmoset brain shares a number of similarities with the human brain, including hierarchically organized sensory. ABSTRACT Animal models represent unique source of in vivo data for various fields of biomedical research.

In today’s pharmaceutical drug development, animal models are used as pre-clinical tools. Metabolomics for Biomedical Research brings together recent progress on study design, analytics, biostatistics and bioinformatics for the success of metabolomics research.

Metabolomics represents a very interdisciplinary research prominent in the functional analyses of living systems; hence, this book focuses on translation and medical aspects.

Research on relevant, carefully designed, well-characterized and controlled animal models will remain for a long time an essential step for fundamental discoveries, for testing hypotheses at the organism level and for the validation of human data.

Animal models must be constantly improved to be more reliable and informative. Get this from a library. Selected abstracts on animal models for biomedical research.

[Institute of Laboratory Animal Resources (U.S.);]. Book: The germ-free animal in biomedical research. pppp. Abstract: The aim of the book is to provide information to the novice on how to derive and use gnotobiotic animals and to help the experienced worker to bring up to date his knowledge of advances in this field.

The validity of animal models of depression CMB_Chindd 14 CMB_Chindd 14 10/23/ AM 10/23/ AM CHAPTER 2 / SELECTION OF BIOMEDICAL ANIMAL MODELS 15 12 Rodent models. In an effort to assist the biomedical researcher in gaining this knowledge, this chapter provides the following key elements: definition of types of animal models, legislative and legal requirements, criteria for choosing a model, extrapolation validity recommendations, and descriptive features for publication.

Published Monday, Aug. 17,am. Front Page» State/National News» Animal Model Research for Veterinarians Ph.D. training program awarded NIH .Animal models have been used in experimental research to increase human knowledge and contribute to finding solutions to biological and biomedical questions.

However, increased concern for the welfare of the animals used, and a growing awareness of the concept of animal rights, has brought a greater focus on the related ethical issues. Domestic animals are unique models for biomedical research due to their long history (thousands of years) of strong phenotypic selection.

This process has enriched for novel mutations that have contributed to phenotype evolution in domestic animals. The characterization of such mutations provides insights in gene function and biological mechanisms.